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IL23R 抗体 (AA 25-233)

This anti-IL23R antibody is a 兔 多克隆 antibody detecting IL23R in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN5519017
发货至: 中国

Quick Overview for IL23R 抗体 (AA 25-233) (ABIN5519017)

抗原

See all IL23R 抗体
IL23R (Interleukin 23 Receptor (IL23R))

适用

  • 51
  • 21
  • 17
  • 1
小鼠, 大鼠

宿主

  • 46
  • 8
  • 4
  • 3

克隆类型

  • 50
  • 11
多克隆

标记

  • 35
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This IL23R antibody is un-conjugated

应用范围

  • 41
  • 20
  • 19
  • 6
  • 6
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-233

    原理

    Anti-IL23 Receptor/Il23r Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-IL23 Receptor/Il23r Antibody Picoband® (ABIN5519017). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse IL23 Receptor recombinant protein (Position: I25-D233).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA (Cap), 1-5 μg/mL
    1. Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. (Dec 2006). "A genome-wide association study identifies IL23R as an inflammatory bowel disease gene". Science. 314 (5804): 1461-3. 2. Momozawa Y, Mni M, Nakamura K, Coppieters W, Almer S, Amininejad L, et al. (Jan 2011). "Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease". Nature Genetics. 43 (1): 43-7.

    说明

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL23R (Interleukin 23 Receptor (IL23R))

    别名

    Il23r

    背景

    Synonyms: Interleukin-23 receptor, IL-23 receptor, IL-23R, Il23r,

    Tissue Specificity: Expressed by Th1, Th2 and dendritic cells.

    Background: Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

    分子量

    58 kDa

    基因ID

    209590

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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