IGFBP3 抗体 (AA 29-268)
Quick Overview for IGFBP3 抗体 (AA 29-268) (ABIN5519005)
抗原
See all IGFBP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-268
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原理
- Anti-IGFBP3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IGFBP3 Antibody Picoband® (ABIN5519005). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat IGFBP3 recombinant protein (Position: A29-K268).
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亚型
- IgG
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anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 186-292) antibody
IGFBP3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 182-291) antibodyIGFBP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 162-189) antibodyIGFBP3 适用: 人, 小鼠, Hamster WB 宿主: 兔 Polyclonal RB28430 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 152-292) antibodyIGFBP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 135-277) antibodyIGFBP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D14 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 137-274) antibodyIGFBP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 106-241) antibodyIGFBP3 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (Ser53) antibodyIGFBP3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 1-291) antibodyIGFBP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 100-200) antibodyIGFBP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL,
1. Lofqvist, C., Chen, J., Connor, K. M., Smith, A. C. H., Aderman, C. M., Liu, N., Pintar, J. E., Ludwig, T., Hellstrom, A., Smith, L. E. H. IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth.Proc. Nat. Acad. Sci. 104: 10589-10594, 2007. 2. Nwosu BU, et al. Evidence of insulin-like growth factor binding protein-3 proteolysis during growth hormone stimulation testing. J Pediatr Endocrinol Metab, 2011. 3. Relationship of insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) gene polymorphism with the susceptibility to development of prostate cancer and influence on serum levels of IGF-I, and IGFBP-3. Safarinejad MR, et al. Growth Horm IGF Res, 2011 Jun. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
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别名
- Igfbp3
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背景
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Synonyms: Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, Igfbp3, Igfbp-3,
Background: IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 40 kDa
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基因ID
- 24484
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UniProt
- P15473
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途径
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
抗原
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