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CD14 抗体 (AA 16-260)

CD14 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518974
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
    抗原表位
    • 16
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
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    • 1
    • 1
    • 1
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    • 1
    AA 16-260
    适用
    • 247
    • 46
    • 30
    • 28
    • 28
    • 28
    • 25
    • 24
    • 22
    • 18
    • 15
    • 14
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    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 204
    • 63
    • 16
    • 3
    • 1
    克隆类型
    • 224
    • 63
    多克隆
    标记
    • 120
    • 29
    • 22
    • 17
    • 13
    • 6
    • 5
    • 4
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD14 antibody is un-conjugated
    应用范围
    • 202
    • 98
    • 61
    • 52
    • 47
    • 45
    • 21
    • 21
    • 20
    • 14
    • 13
    • 13
    • 7
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for CD14 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for CD14 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.
    Gene Name: CD14 antigen
    Protein Name: Monocyte differentiation antigen CD14
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived mouse CD14 recombinant protein (Position: S16-A260).
    亚型
    IgG
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wu, Yang, Qi, Zhou, Hu, Wang: "ANTI-INFLAMMATORY ACTIVITY OF PLATYCODIN D ON ALCOHOL-INDUCED FATTY LIVER RATS VIA TLR4-MYD88-NF-κB SIGNAL PATH." in: African journal of traditional, complementary, and alternative medicines : AJTCAM, Vol. 13, Issue 4, pp. 176-183, (2017) (PubMed).

    Wu, Liu, Zhang, Xing, Zheng, Ji: "Chinese medicinal formula, Qinggan Huoxue Recipe protects rats from alcoholic liver disease via the lipopolysaccharide-Kupffer cell signal conduction pathway." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 363-370, (2014) (PubMed).

    Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

    Zhao, Zhao, Feng, Zhang, Zhuang, Zhao, Li, Li, Liu: "Detection of vulnerable atherosclerotic plaque and prediction of thrombosis events in a rabbit model using 18F-FDG -PET/CT." in: PLoS ONE, Vol. 8, Issue 4, pp. e61140, (2013) (PubMed).

  • 抗原
    CD14
    别名
    Cd14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景
    CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

    Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Cd14
    基因ID
    12475
    UniProt
    P10810
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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