我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PPARG 抗体 (Middle Region)

Name: PPARG 抗体 (Middle Region)
SKU: ABIN5518944
Availability: OutOfStock

This 兔多克隆 antibody specifically detects PPARG in WB. It exhibits reactivity toward 人. It has been mentioned in 6+ publications

Western blot analysis of PPAR gamma using anti-PPAR gamma antibody (ABIN5518944). (PPARG 抗体 (Middle Region))

Western blot analysis of PPAR gamma using anti-PPAR gamma antibody . (PPARG 抗体 (Middle Region))

2 images

(6 references)

产品编号 ABIN5518944

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PPARG 抗体 (Middle Region) (ABIN5518944)

抗原

See all PPARG 抗体

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PPARG antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PPARG Primary Antibody

抗原表位
28

27

16

16

16

13

12

11

9

5

5

4

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region

原理

Anti-PPAR gamma/PPARG Antibody

序列

AIRFGRMPQA EKEKLLAEIS SDIDQLNPES ADLRALAKHL YD

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins.

预测反应

identical to the related mouse,rat sequences.

产品特性

Anti-PPAR gamma/PPARG Antibody. Tested in WB applications. This antibody reacts with Human.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human PPAR gamma, identical to the related mouse and rat sequences.

亚型

IgG
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 315-420) antibody
PPARG 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 101-200) antibody
PPARG 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 149-273) antibody
PPARG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer273) antibody
PPARG 适用: 人, 小鼠, 大鼠, 绵羊, 豚鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 1-30), (N-Term) antibody
PPARG 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22139 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibody
PPARG 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 8D1H8F4 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 311-493) antibody
PPARG 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal C5 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 349-488) antibody
PPARG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human

说明

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Yang, Fu, Hu, Luo, Hu, Wang: "PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis." in: Experimental & molecular medicine, Vol. 50, Issue 1, pp. e431, (2018) (PubMed).

Wu, Wu, Jiao, Wang, Wang, Zhang: "Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood-brain barrier disruption in rabbits." in: BMC neurology, Vol. 15, pp. 37, (2016) (PubMed).

Chen, Bai, Liao, Peng, Wu, Wang, Zeng, Xie: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).

Wang, Liu, Dang, Ma, Zhang, Wang: "The effect of core decompression on local expression of BMP-2, PPAR-γ and bone regeneration in the steroid-induced femoral head osteonecrosis." in: BMC musculoskeletal disorders, Vol. 13, pp. 142, (2012) (PubMed).

Xie, Wang, Zhang, Li, Can, Qing, Kung, Zhang: "Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice." in: Experimental and therapeutic medicine, Vol. 2, Issue 2, pp. 309-315, (2012) (PubMed).

Xie, Zhao, Gu, Du, Cai, Zhang: "Scorpion in Combination with Gypsum: Novel Antidiabetic Activities in Streptozotocin-Induced Diabetic Mice by Up-Regulating Pancreatic PPARγ and PDX-1 Expressions." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2011, pp. 683561, (2011) (PubMed).
抗原

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

别名

PPARG

背景

Background: The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha, and PPAR delta, encoded by different genes. PPARs are ligand-regulated transcription factors that control gene expression by binding to specific response elements (PPREs) within promoters. PPAR gamma is a transcription factor that has a pivotal role in adipocyte differentiation and expression of adipocyte-specific genes. The PPAR gamma1 and gamma2 isoforms result from alternative splicing and have ligand-dependent and -independent activation domains. PPAR gamma is a member of a family of nuclear receptors/ligand-dependent transcription factors, which bind to hormone response elements on target gene promoters. PPAR gamma is abundantly expressed in normal lung tissues, especially in endothelial cells, but that its expression is reduced or absent in the angiogenic plexiform lesions of pulmonary hypertensive lungs and in the vascular lesions of a rat model of severe pulmonary hypertension. And it is concluded that fluid shear stress decreases the expression of PPARgamma in endothelial cells and that loss of PPARgamma expression characterizes an abnormal, proliferating, apoptosis-resistant endothelial cell phenotype.
Gene Full Name: peroxisome proliferator activated receptor gamma

分子量

58 kDa

基因ID

5468

UniProt

P37231

途径

MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation