RANBP1 抗体 (AA 2-201)
Quick Overview for RANBP1 抗体 (AA 2-201) (ABIN5518868)
抗原
See all RANBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-201
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原理
- Anti-RanBP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RanBP1 Antibody Picoband® (ABIN5518868). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RanBP1 recombinant protein (Position: A2-Q201). Human RanBP1 shares 93.1% amino acid (aa) sequence identity with mouse RanBP1.
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亚型
- IgG
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anti-RAN Binding Protein 1 (RANBP1) (C-Term) antibody
Verified RANBP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) antibodyKO Validated RANBP1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 3-165) antibodyRANBP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 52-111) antibodyRANBP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (N-Term) antibodyRANBP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 1-187), (N-Term) antibodyRANBP1 适用: 人, 小鼠, 大鼠, Cow WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 86-116) antibodyRANBP1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (C-Term) antibodyRANBP1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 1-201) antibodyRANBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 1-100) antibodyRANBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Hayashi N, Yokoyama N, Seki T, Azuma Y, Ohba T, Nishimoto T (August 1995). "RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4". Mol Gen Genet. 247 (6): 661-9. 2. Kehlenbach RH, Dickmanns A, Kehlenbach A, Guan T, Gerace L (July 1999). "A Role for RanBP1 in the Release of CRM1 from the Nuclear Pore Complex in a Terminal Step of Nuclear Export". J Cell Biol. 145 (4): 645-57. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RANBP1 (RAN Binding Protein 1 (RANBP1))
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别名
- RANBP1
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背景
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Synonyms: Ran-specific GTPase-activating protein,Ran-binding protein 1,RanBP1,RANBP1,
Tissue Specificity: Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.
Background: Ran-specific binding protein 1 is an enzyme that in humans is encoded by the RANBP1 gene. This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants.
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分子量
- 27 kDa
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基因ID
- 5902
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UniProt
- P43487
抗原
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