NCKAP1 抗体 (AA 2-201)
Quick Overview for NCKAP1 抗体 (AA 2-201) (ABIN5518856)
抗原
See all NCKAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-201
-
原理
- Anti-NCKAP1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-NCKAP1 Antibody Picoband® (ABIN5518856). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human NCKAP1 recombinant protein (Position: S2-K201). Human NCKAP1 shares 98.5% and 98% amino acid (aa) sequence identity with mouse and rat NCKAP1, respectively.
-
亚型
- IgG
-
-
anti-NCK Associated Protein 1 (NCKAP1) antibody
NCKAP1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) antibodyNCKAP1 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) antibodyNCKAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NCK Associated Protein 1 (NCKAP1) (AA 1-250) antibodyNCKAP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW (Aug 2002). "Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck". Nature. 418 (6899): 790-3. 2. Kitamura Y, Kitamura T, Sakaue H, Maeda T, Ueno H, Nishio S, Ohno S, Osada SI, Sakaue M, Ogawa W, Kasuga M (Mar 1997). "Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac". The Biochemical Journal. 322 (Pt 3): 873-8. 3. Suzuki, T., Nishiyama, K., Yamamoto, A., Inazawa, J., Iwaki, T., Yamada, T., Kanazawa, I., Sakaki, Y. Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease. Genomics 63: 246-254, 2000. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
-
别名
- NCKAP1
-
背景
-
Synonyms: Nck-associated protein 1,NAP 1,Membrane-associated protein HEM-2,p125Nap1,NCKAP1,HEM2, KIAA0587, NAP1,
Tissue Specificity: Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.
Background: Nck-associated protein 1 is a protein that in humans is encoded by the NCKAP1 gene. By somatic cell hybrid analysis, the NCKAP1 gene was mapped to chromosome 2. NCKAP1 is a predicted type II transmembrane protein, with a C-terminal transmembrane domain. It was demonstrated that suppression of NCKAP1 expression using an antisense NCKAP1 oligonucleotide induced apoptosis of neuronal cells.
-
分子量
- 129 kDa
-
基因ID
- 10787
-
UniProt
- Q9Y2A7
-
途径
- RTK signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
抗原
-
