CD31 抗体 (C-Term)
(37 references)Quick Overview for CD31 抗体 (C-Term) (ABIN5518694)
抗原
See all CD31 (PECAM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 717-732, C-Term
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原理
- Anti-CD31/PECAM1 Antibody Picoband®
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序列
- RKAVPDAVES RYSRTE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CD31/PECAM1 Antibody (ABIN5518694). Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CD31.
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亚型
- IgG
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 601-680) antibody
PECAM1 适用: 人, 小鼠, 大鼠, 兔, Pig, 犬 FACS, WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (C-Term) antibodyPECAM1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC (p), IHC (f) 宿主: 山羊 Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-382) antibodyPECAM1 适用: 人 FACS, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 681-738) antibodyPECAM1 适用: 人, 小鼠, 大鼠, 兔, Pig, Cow FACS, WB, ELISA, IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-315) antibodyPECAM1 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 9E6E12 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) antibodyPECAM1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1D2-1A5 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 适用: 人, 兔, Cynomolgus FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal JC-70A unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 适用: 人, 大鼠 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal C31-3 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 625-738) antibodyPECAM1 适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal PECAM1-3527 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 适用: 人, 大鼠, 兔, Cynomolgus FACS, WB, IHC, StM 宿主: 小鼠 Monoclonal C31-7 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
1. Gumina, R. J., Kirschbaum, N. E., Rao, P. N., vanTuinen, P., Newman, P. J.The human PECAM1 gene maps to 17q23.Genomics 34: 229-232, 1996. 2. Newman, P. J., Berndt, M. C., Gorski, J., White, G. C., II, Lyman, S., Paddock, C., Muller, W. A.PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.Science 247: 1219-1222, 1990. 3. Xie, Y., Muller, W. A.Fluorescence in situ hybridization mapping of the mouse platelet endothelial cell adhesion molecule-1 (PECAM1) to mouse chromosome 6, region F3-G1.Genomics 37: 226-228, 1996. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex." in: Oncotarget, Vol. 7, Issue 49, pp. 80716-80734, (2018) (PubMed).
: "Peroxisome proliferator‑activated receptor γ mediates porcine placental angiogenesis through hypoxia inducible factor‑, vascular endothelial growth factor‑ and angiopoietin‑mediated signaling." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 2636-2644, (2018) (PubMed).
: "MicroRNA-210 promotes angiogenesis in acute myocardial infarction." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5658-5665, (2018) (PubMed).
: "Re: Treatment of Diabetes Mellitus-Induced Erectile Dysfunction Using Endothelial Progenitor Cells Genetically Modified with Human Telomerase Reverse Transcriptase." in: The Journal of urology, Vol. 197, Issue 2, pp. 494, (2017) (PubMed).
: "Angiogenic gene-modified myoblasts promote vascularization during repair of skeletal muscle defects." in: Journal of tissue engineering and regenerative medicine, Vol. 9, Issue 12, pp. 1404-16, (2016) (PubMed).
: "ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer." in: Oncotarget, Vol. 6, Issue 9, pp. 6959-76, (2016) (PubMed).
: "Wound Dressing Model of Human Umbilical Cord Mesenchymal Stem Cells-Alginates Complex Promotes Skin Wound Healing by Paracrine Signaling." in: Stem cells international, Vol. 2016, pp. 3269267, (2016) (PubMed).
: "Preclinical pharmacodynamic evaluation of antibiotic nitroxoline for anticancer drug repurposing." in: Oncology letters, Vol. 11, Issue 5, pp. 3265-3272, (2016) (PubMed).
: "Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cultivated in serum-free medium." in: Oncology letters, Vol. 12, Issue 2, pp. 815-824, (2016) (PubMed).
: "Xenotransplantation of human adipose-derived stem cells in zebrafish embryos." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123264, (2015) (PubMed).
: "Inhibition of Janus kinase-2 signalling pathway ameliorates portal hypertensive syndrome in partial portal hypertensive and liver cirrhosis rats." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 47, Issue 4, pp. 315-23, (2015) (PubMed).
: "Fluid and cell behaviors along a 3D printed alginate/gelatin/fibrin channel." in: Biotechnology and bioengineering, Vol. 112, Issue 8, pp. 1683-95, (2015) (PubMed).
: "MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling." in: Oncogene, Vol. 34, Issue 15, pp. 1968-78, (2015) (PubMed).
: "Expression and function of the ID1 gene during transforming growth factor-?1-induced differentiation of human embryonic stem cells to endothelial cells." in: Cellular reprogramming, Vol. 17, Issue 1, pp. 59-68, (2015) (PubMed).
: "Distinct molecular basis for endothelial differentiation: gene expression profiles of human mesenchymal stem cells versus umbilical vein endothelial cells." in: Cellular immunology, Vol. 289, Issue 1-2, pp. 7-14, (2014) (PubMed).
: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, (2014) (PubMed).
: "Construction of tissue-engineered bone using a bioreactor and platelet-rich plasma." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 413-418, (2014) (PubMed).
: "SKLB-M8 induces apoptosis through the AKT/mTOR signaling pathway in melanoma models and inhibits angiogenesis with decrease of ERK1/2 phosphorylation." in: Journal of pharmacological sciences, Vol. 126, Issue 3, pp. 198-207, (2014) (PubMed).
: "Different angiogenic abilities of self-setting calcium phosphate cement scaffolds consisting of different proportions of fibrin glue." in: BioMed research international, Vol. 2014, pp. 785146, (2014) (PubMed).
: "Promoted regeneration of mature blood vessels by electrospun fibers with loaded multiple pDNA-calcium phosphate nanoparticles." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fu?r Pharmazeutische Verfahrenstechnik e.V, Vol. 85, Issue 3 Pt A, pp. 699-710, (2013) (PubMed).
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: "The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex." in: Oncotarget, Vol. 7, Issue 49, pp. 80716-80734, (2018) (PubMed).
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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别名
- PECAM1
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背景
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Synonyms: Platelet endothelial cell adhesion molecule,PECAM-1,EndoCAM,GPIIA',PECA1,CD31,PECAM1,
Tissue Specificity: Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Isoform Long predominates in all tissues examined. Isoform Delta12 is detected only in trachea. Isoform Delta14-15 is only detected in lung. Isoform Delta14 is detected in all tissues examined with the strongest expression in heart. Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U-937 histiocytic lymphoma cell lines (at protein level). .
Background: PECAM-1 (Platelet endothelial cell adhesion molecule), also known as cluster of differentiation 31 (CD31) is a protein that in human is encoded by the PECAM1 gene found on chromosome 17. PECAM1 is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. Using a PCR-based analysis of somatic cell hybrids, Gumina et al. (1996) mapped PECAM1 to chromosome 17 in the region 17q23-qter. Several adhesion molecules expressed on platelets and endothelium also localized to 17q. Xie and Muller (1996) mapped the Pecam1 gene to mouse chromosome 6, region F3-G1, by fluorescence in situ hybridization. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions, and PECAM-1 plays a key role in removing aged neutrophils from the body.
Sequence Similarities: Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
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分子量
- 120 kDa
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UniProt
- P16284
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途径
- Regulation of Actin Filament Polymerization
抗原
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