JUP 抗体 (N-Term)
Quick Overview for JUP 抗体 (N-Term) (ABIN5518649)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-118, N-Term
-
原理
- Anti-gamma Catenin/JUP Antibody Picoband®
-
序列
- LLATQVEGQA TNLQRLAE
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-gamma Catenin/JUP Antibody (ABIN5518649). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human gamma Catenin, different from the related mouse and rat sequences by one amino acid.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Kolligs, F. T., Kolligs, B., Hajra, K. M., Hu, G., Tani, M., Cho, K. R., Fearon, E. R. : Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev. 14: 1319-1331, 2000. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Sodium azide, Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- JUP (Junction Plakoglobin (JUP))
-
别名
- JUP
-
背景
-
Synonyms: Junction plakoglobin,Catenin gamma,Desmoplakin III,Desmoplakin-3,JUP,CTNNG, DP3,
Tissue Specificity: Widely expressed, with highest levels in heart, brain, and skeletal muscle. .
Background: Cateningamma, also known as junction plakoglobin (JUP) or plakoglobin (PKGB). Plakoglobin is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Cateninbeta and cateningamma (plakoglobin), vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. Cateningamma may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
Sequence Similarities: Belongs to the beta-catenin family.
-
分子量
- 82 kDa
-
UniProt
- P14923
-
途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
-