COBRA1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for COBRA1 抗体 (N-Term) (ABIN5518104)
抗原
See all COBRA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- NELFB Antibody - N-terminal region
-
序列
- NCTEPLKAIE QFQTENGVLL PSLQSALPFL DLHGTPRLEF HQSVFDELRD
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 90%
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human COBRA1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65310-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- COBRA1 (Cofactor of BRCA1 (COBRA1))
-
别名
- NELFB
-
背景
-
Background Information: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2, MIM 606026), either NELFC or NELFD (TH1L, MIM 605297), and NELFE (RDBP, MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1, MIM 603555) and SPT5 (SUPT5H, MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]
Gene Name: negative elongation factor complex member B
Alternative Symbols: COBRA1, NELF-B
Protein Name: negative elongation factor B
-
分子量
- 66 kDa
-
基因ID
- 25920
-
NCBI登录号
- NP_056271
-
UniProt
- Q8WX92
抗原
-