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- 抗原 See all COBRA1 抗体
- COBRA1 (Cofactor of BRCA1 (COBRA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This COBRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-COBRA 1 antibody was Protein G purified from culture supernatant. This antibody is directed against human COBRA 1. Reactivity is expected against mouse and rat sources. Cross-reactivity from other sources has not been determined.
- 免疫原
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Immunogen: Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli.
Immunogen Type: Recombinant Protein
- 克隆位点
- F7E4
- 亚型
- IgG1
- Top Product
- Discover our top product COBRA1 Primary Antibody
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anti-Cofactor of BRCA1 (COBRA1) (Center) antibody
COBRA1 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 8-199) antibodyCOBRA1 适用: 人 WB, ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) (AA 1-475) antibodyCOBRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
anti-Cofactor of BRCA1 (COBRA1) antibodyCOBRA1 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal F7E4 unconjugated
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- 应用备注
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Application Note: Anti-COBRA 1 antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 62 kDa in size corresponding to COBRA1 proteins in neonatal rat brain lysate or other appropriate lysates.
ELISA Dilution: 1:10,000
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- 抗原
- COBRA1 (Cofactor of BRCA1 (COBRA1))
- 别名
- COBRA 1 (COBRA1 产品)
- 别名
- LOC100219583 antibody, COBRA1 antibody, NELF-B antibody, bZ1O1.4 antibody, cobra1 antibody, cobra2 antibody, fe01e12 antibody, wu:fe01e12 antibody, zgc:55628 antibody, MGC131073 antibody, Cobra1 antibody, RGD1307832 antibody, A730008L03Rik antibody, AB041607 antibody, AI663983 antibody, Nelf-b antibody, cofactor of BRCA1 antibody, negative elongation factor complex member B antibody, negative elongation factor complex member B L homeolog antibody, LOC100219583 antibody, NELFB antibody, nelfb antibody, nelfb.L antibody, Nelfb antibody
- 背景
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Synonyms: COBRA1, Negative elongation factor B, NELF-B, Cofactor of BRCA1
Background: COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: COBRA1
- 基因ID
- 25920
- UniProt
- Q8WX92
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