GSAP 抗体 (N-Term)
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Quick Overview for GSAP 抗体 (N-Term) (ABIN5517988)
抗原
See all GSAP (PION) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QTRQNELLYT FEKDLQVFSC SVNSERTLLA ASLVQSTKEG KRNELQPGSK
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预测反应
- Cow: 85%, Dog: 85%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against GSAP. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSAP
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anti-Pigeon Homolog (PION) (AA 616-854) antibody
PION 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pigeon Homolog (PION) (AA 536-565), (C-Term) antibodyPION 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Pigeon Homolog (PION) (C-Term) antibodyPION 适用: 人, 大鼠, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GSAP (PION) (Pigeon Homolog (PION))
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别名
- GSAP
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背景
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Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease. Formation of amyloid-beta is catalyzed by gamma-secretase, a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein C-terminal fragment (APP-CTF).
Alias Symbols: GSAP, PION,
Protein Size: 854 -
基因ID
- 54103
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NCBI登录号
- NP_059135
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UniProt
- A4D1B5
抗原
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