Phospholipase C gamma 1 抗体 (C-Term)
Quick Overview for Phospholipase C gamma 1 抗体 (C-Term) (ABIN5517384)
抗原
See all Phospholipase C gamma 1 (PLCG1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RGIVCPFVEI EVAGAEYDST KQKTEFVVDN GLNPVWPAKP FHFQISNPEF
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PLCG1. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLCG1
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anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibody
PLCG1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1091-1290) antibodyPLCG1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr771) antibodyPLCG1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibodyPLCG1 适用: 人, 大鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3C2D11 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 39-181) antibodyPLCG1 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2F3D11 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr783) antibodyPLCG1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr783) antibodyPLCG1 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (Tyr771) antibodyPLCG1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 456-488) antibodyPLCG1 适用: 人 WB 宿主: 兔 Polyclonal RB53783 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr771) antibodyPLCG1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
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别名
- PLCG1
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背景
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The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PLC1
Protein Interaction Partner: EGFR, UBC, SARNP, WDR61, RIC8A, AASDHPPT, UBR7, EHD4, DPP7, GTF3C4, LIMD1, RPL38, PYGB, ZAP70, KHDRBS1, RASA1, JAK2, JAK1, LCP2, ERBB3, ERBB2, CBL, LAT, VAV1, PDGFRB, INSR, IRS2, NTMT1, SPRY1, NPM1, NCAM1, ALK, PML, IBTK, EEF1A1, BLNK, BAG3, EPOR, CAMK2A,
Protein Size: 1290 -
基因ID
- 5335
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UniProt
- P19174
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途径
- RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
抗原
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