CD70 抗体 (C-Term)
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Quick Overview for CD70 抗体 (C-Term) (ABIN5516679)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RLSFHQGCTI ASQRLTPLAR GDTLCTNLTG TLLPSRNTDE TFFGVQWVRP
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预测反应
- Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 79%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against CD70. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD70
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Alias Symbols: CD27L, CD27LG, TNFSF7
Protein Interaction Partner: UBC, CD27, ELAVL1,
Protein Size: 193 -
基因ID
- 970
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NCBI登录号
- NP_001243
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
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