MAP3K7 抗体 (C-Term)
Quick Overview for MAP3K7 抗体 (C-Term) (ABIN5516090)
抗原
See all MAP3K7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VTGTEPGQVS SRSSSPSVRM ITTSGPTSEK PTRSHPWTPD DSTDTNGSDN
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产品特性
- This is a rabbit polyclonal antibody against MAP3K7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP3K7
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody
MAP3K7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 300-470) antibodyMAP3K7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Internal Region) antibodyVerified MAP3K7 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Thr187) antibodyMAP3K7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 471-579) antibodyMAP3K7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pSer412) antibodyMAP3K7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 471-579) antibodyMAP3K7 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E8H4 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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别名
- MAP3K7
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背景
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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MAP3K7, TAK1,
Protein Interaction Partner: MAGED1, UBC, TRAF6, HSPB1, TAB2, IKBKB, TRAF4, TGFBR1, MAP3K7, MAP2K6, MAPK8, NAIP, XIAP, RIPK1, TIRAP, TAB1, SIK1, SIK3, SYK, SASH1, IRAK1, TNFRSF1A, MAPK8IP1, RIPK2, IKBKG, VRK2, MAP2K4, NOD2, PRKCQ, PPM1L, SKIL, PPP6C, PPP2R1A, MAP3K3, BST2, PINK1, MAL
Protein Size: 579 -
基因ID
- 6885
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途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
抗原
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