CLK2 抗体 (C-Term)
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Quick Overview for CLK2 抗体 (C-Term) (ABIN5515887)
抗原
See all CLK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against CLK2. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CLK2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CLK2 (CDC-Like Kinase 2 (CLK2))
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别名
- CLK2
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背景
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This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Alias Symbols: CLK2,
Protein Interaction Partner: TRIM27, ECE1, CLK3, CLK2, YTHDC1, PRPF38A, LNX1, ZNF394, CPSF7, SNIP1, GMCL1, ZNF398, RSRP1, LUZP4, MRPL4, ZNF473, KLHL2, RNPS1, SRRM1, ZNF263, RBM39, ZRSR2, UBE2I, U2AF1, SRPK2, SDCBP, EED, ZNF30, FIP1L1, LUC7L, ZCCHC8, WDR33, CPSF2, PPHLN1, CPSF1, SETD2
Protein Size: 499 -
基因ID
- 1196
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NCBI登录号
- XP_005276799
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UniProt
- P49760
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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