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CLK2 抗体 (AA 240-499)

CLK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150731
发货至: 中国
  • 抗原 See all CLK2 抗体
    CLK2 (CDC-Like Kinase 2 (CLK2))
    抗原表位
    • 15
    • 13
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 240-499
    适用
    • 50
    • 37
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 64
    克隆类型
    • 64
    多克隆
    标记
    • 25
    • 6
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLK2 antibody is un-conjugated
    应用范围
    • 63
    • 37
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Dual specificity protein kinase CLK2 protein (240-499AA)
    亚型
    IgG
    Top Product
    Discover our top product CLK2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CLK2 (CDC-Like Kinase 2 (CLK2))
    别名
    CLK2 (CLK2 产品)
    别名
    MGC53993 antibody, hclk2 antibody, clk2 antibody, fb20c02 antibody, si:ch211-81a5.7 antibody, wu:fb20c02 antibody, MGC131228 antibody, hCLK2 antibody, AU041688 antibody, Tu52 antibody, CDC like kinase 2 antibody, CDC like kinase 2 S homeolog antibody, CDC-like kinase 2a antibody, CDC like kinase 2 L homeolog antibody, CDC-like kinase 2 antibody, CLK2 antibody, clk2.S antibody, clk2 antibody, clk2a antibody, clk2.L antibody, Clk2 antibody
    背景

    Background: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B thereby stimulating the assembly of PP2A phosphatase with the PPP2R5B-AKT1 complex leading to dephosphorylation of AKT1. Phosphorylates: PTPN1, SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.

    Aliases: CDC like kinase 2 antibody, CDC-like kinase 2 antibody, CLK 2 antibody, CLK kinase antibody, CLK2 antibody, Clk2 Scamp3 antibody, CLK2_HUMAN antibody, Dual specificity protein kinase CLK2 antibody, hCLK 2 antibody, hCLK2 antibody, Tu52 antibody

    UniProt
    P49760
    途径
    Regulation of Carbohydrate Metabolic Process
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