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CLK2 抗体 (N-Term)

CLK2 适用: 人 WB 宿主: 兔 Polyclonal RB3205 unconjugated
产品编号 ABIN391766
发货至: 中国
  • 抗原 See all CLK2 抗体
    CLK2 (CDC-Like Kinase 2 (CLK2))
    抗原表位
    • 15
    • 12
    • 9
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 50
    • 37
    • 22
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 64
    克隆类型
    • 64
    多克隆
    标记
    • 25
    • 6
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLK2 antibody is un-conjugated
    应用范围
    • 63
    • 38
    • 13
    • 13
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CLK2.
    克隆位点
    RB3205
    亚型
    Ig Fraction
    Top Product
    Discover our top product CLK2 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Yoshida, Kim, Carver, Su, Weremowicz, Mulvey, Yamamoto, Brennan, Mei, Long, Yao, Polyak: "CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer." in: Cancer research, Vol. 75, Issue 7, pp. 1516-26, (2015) (PubMed).

    Nam, Seo, Park, An, Kim, Yang, Kim, Jeong, Jin: "Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31157-63, (2010) (PubMed).

  • 抗原
    CLK2 (CDC-Like Kinase 2 (CLK2))
    别名
    CLK2 (CLK2 产品)
    别名
    MGC53993 antibody, hclk2 antibody, clk2 antibody, fb20c02 antibody, si:ch211-81a5.7 antibody, wu:fb20c02 antibody, MGC131228 antibody, hCLK2 antibody, AU041688 antibody, Tu52 antibody, CDC like kinase 2 antibody, CDC like kinase 2 S homeolog antibody, CDC-like kinase 2a antibody, CDC like kinase 2 L homeolog antibody, CDC-like kinase 2 antibody, CLK2 antibody, clk2.S antibody, clk2 antibody, clk2a antibody, clk2.L antibody, Clk2 antibody
    背景
    This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.
    分子量
    60090
    基因ID
    1196
    NCBI登录号
    NP_003984
    UniProt
    P49760
    途径
    Regulation of Carbohydrate Metabolic Process
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