ABI1 抗体 (N-Term)
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Quick Overview for ABI1 抗体 (N-Term) (ABIN5515797)
抗原
See all ABI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MAELQMLLEE EIPSGKRALI ESYQNLTRVA DYCENNYIQA TDKRKALEET
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against ABI1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ABI1
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anti-Abl-Interactor 1 (ABI1) (AA 1-182) antibody
ABI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 180-230) antibodyABI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 151-175), (N-Term) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 483-494), (C-Term) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 81-108), (N-Term) antibodyABI1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22014 unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 87-117), (N-Term) antibodyABI1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (AA 81-108) antibodyABI1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) (C-Term) antibodyABI1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 1 (ABI1) antibodyABI1 适用: 人, 小鼠, Hamster WB, IP, IHC (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ABI1 (Abl-Interactor 1 (ABI1))
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别名
- ABI1
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背景
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This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
Alias Symbols: ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1
Protein Interaction Partner: ABL1, UBC, PRPF40A, TCERG1, GAS7, APBB1, SRRM1, PRKAA1, PIK3R1, CDC123, CTTN, NCK2, NCK1, CBL, CACNA1A, RYK, EPS8L1, ENAH, MINK1, EVL, NIN, CYFIP2, HSPA8, WASF2, WASF1, PAK2, NCKAP1, ABI1, VASP, SOS2, EPS8, NCF1, SPTA1, SPTAN1, SOS1, NEB, EPS8L3, EPS8L2,
Protein Size: 508 -
基因ID
- 10006
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NCBI登录号
- NM_005470, NP_005461
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UniProt
- Q8IZP0
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途径
- RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
抗原
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