PSMA7 抗体 (C-Term)
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北京 101111
Quick Overview for PSMA7 抗体 (C-Term) (ABIN5515527)
抗原
See all PSMA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VQSGGKNIEL AVMRRDQSLK ILNPEEIEKY VAEIEKEKEE NEKKKQKKAS
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PSMA7
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
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别名
- PSMA7
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背景
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.
Alias Symbols: C6, HSPC, RC6-1, XAPC7
Protein Size: 167 -
基因ID
- 5688
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NCBI登录号
- NM_002792, NP_002783
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UniProt
- O14818
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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