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CYBB 抗体 (C-Term)

This anti-CYBB antibody is a 兔 多克隆 antibody detecting CYBB in WB. Suitable for 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠 和 马.
产品编号 ABIN5515414
发货至: 中国

Quick Overview for CYBB 抗体 (C-Term) (ABIN5515414)

抗原

See all CYBB 抗体
CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

适用

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人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马

宿主

  • 60
  • 8
  • 2

克隆类型

  • 51
  • 19
多克隆

标记

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  • 2
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  • 1
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This CYBB antibody is un-conjugated

应用范围

  • 46
  • 24
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  • 9
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Western Blotting (WB)
  • 抗原表位

    • 16
    • 9
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    • 1
    • 1
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    C-Term

    序列

    GRPNWDNEFK TIASQHPNTR IGVFLCGPEA LAETLSKQSI SNSESGPRGV

    预测反应

    Cow: 85%, Dog: 93%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against CYBB. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYBB
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

    别名

    CYBB

    背景

    Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

    Alias Symbols: AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX

    Protein Interaction Partner: IQGAP1, ACTB, UBC, SUMO1, RAC1, NCF4, NCF2, NCF1, CYBA, ACTG1,

    Protein Size: 570

    基因ID

    1536

    NCBI登录号

    NM_000397, NP_000388

    UniProt

    P04839
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