HRH1 抗体 (C-Term)
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Quick Overview for HRH1 抗体 (C-Term) (ABIN5514867)
抗原
See all HRH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SSWPSPTEPS SKSGNLRHLH ILIGTSVVKI PFTILLFFLL HRWCSNKKKC
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预测反应
- Human: 100%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HRH1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HRH1 (Histamine Receptor H1 (HRH1))
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别名
- HRH1
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背景
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Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: H1R, H1-R, HH1R, hisH1
Protein Interaction Partner: UBC,
Protein Size: 487 -
基因ID
- 3269
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NCBI登录号
- NM_000861, NP_000852
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UniProt
- P35367
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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