Growth Hormone Receptor 抗体 (N-Term)
Quick Overview for Growth Hormone Receptor 抗体 (N-Term) (ABIN5514835)
抗原
See all Growth Hormone Receptor (GHR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LLTLALAGSS DAFSGSEATA AILSRAPWSL QSVNPGLKTN SSKEPKFTKC
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预测反应
- Horse: 83%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against GHR. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GHR
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anti-Growth Hormone Receptor (GHR) (AA 101-200) antibody
GHR 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 353-588) antibodyGHR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) antibodyGHR 适用: 人 ELISA, IHC, IF 宿主: 兔 Monoclonal 10C11 unconjugated Recombinant Antibody
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Growth Hormone Receptor (GHR) (AA 315-574) antibodyGHR 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 36-266) antibodyGHR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (N-Term) antibodyGHR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-184) antibodyGHR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 36-85) antibodyGHR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Growth Hormone Receptor (GHR)
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别名
- GHR
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背景
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This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: GHR,
Protein Interaction Partner: FBXW11, JAK2, GHR, GH1, BTRC, UBC, SKP1, SOCS2, STUB1, PTPRH, PTPRB, PTPN13, PTPN9, PTPN3, PTPN2, PTPN1, DUSP7, NCOA6, STAT5B, SOCS3, SOCS1, SGTA, CISH, GRB10, STAT5A, AP2A1, SHC1, TYK2, PTPN6, PTPN11, PRLR, PIK3R1, JAK1, IRS1, GH2, GRB2, STAT3, PLCG1,
Protein Size: 297 -
基因ID
- 2690
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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