TFAM 抗体 (AA 1-246)
Quick Overview for TFAM 抗体 (AA 1-246) (ABIN520832)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-246
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原理
- Mouse polyclonal antibody raised against a full-length human TFAM protein.
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序列
- MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE QMIEVGRKDL LRRTIKKQRK YGAEEC
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交叉反应
- 人
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产品特性
- Antibody reactive against mammalian transfected lysate.
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免疫原
- TFAM (NP_003192.1, 1 a.a. ~ 246 a.a) full-length human protein.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- In 1x PBS, pH 7.4
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注意事项
- Aliquot to avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Decreased mitochondrial copy numbers in oral squamous cell carcinoma." in: Head & neck, Vol. 38, Issue 8, pp. 1170-5, (2016) (PubMed).
: "AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway." in: International journal of oncology, Vol. 50, Issue 1, pp. 23-30, (2016) (PubMed).
: "Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells." in: Scientific reports, Vol. 5, pp. 12876, (2015) (PubMed).
: "Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair." in: DNA repair, Vol. 16, pp. 44-53, (2014) (PubMed).
: "Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 12, pp. 5122-35, (2014) (PubMed).
: "Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors." in: Human molecular genetics, Vol. 22, Issue 24, pp. 4871-87, (2013) (PubMed).
: "Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 32, pp. E2967-76, (2013) (PubMed).
: "Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E731-9, (2012) (PubMed).
: "Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2334-46, (2010) (PubMed).
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Decreased mitochondrial copy numbers in oral squamous cell carcinoma." in: Head & neck, Vol. 38, Issue 8, pp. 1170-5, (2016) (PubMed).
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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别名
- TFAM
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背景
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Full Gene Name: transcription factor A, mitochondrial
Synonyms: MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA -
基因ID
- 7019
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NCBI登录号
- NM_003201
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途径
- Chromatin Binding
抗原
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