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TFAM 抗体 (AA 1-246)

Name: TFAM 抗体 (AA 1-246)
SKU: ABIN520832
Availability: OutOfStock

This anti-TFAM antibody is a 小鼠多克隆 antibody detecting TFAM in WB, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 9+ publications.

Western Blot analysis of TFAM expression in transfected 293T cell line by TFAM MaxPab polyclonal antibody. (TFAM 抗体 (AA 1-246))

TFAM MaxPab polyclonal antibody. (TFAM 抗体 (AA 1-246))

Immunofluorescence of purified MaxPab antibody to TFAM on HeLa cell. (TFAM 抗体 (AA 1-246))

Immunoperoxidase of purified MaxPab antibody to TFAM on formalin-fixed paraffin-embedded human small Intestine. (TFAM 抗体 (AA 1-246))

ISt

4 images

(9 references)

产品编号 ABIN520832

发货至: 中国

Quick Overview for TFAM 抗体 (AA 1-246) (ABIN520832)

抗原

See all TFAM 抗体

TFAM (Transcription Factor A, Mitochondrial (TFAM))

适用

人

宿主

小鼠

克隆类型

多克隆

标记

This TFAM antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product TFAM Primary Antibody

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AA 1-246

原理

Mouse polyclonal antibody raised against a full-length human TFAM protein.

序列

MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE QMIEVGRKDL LRRTIKKQRK YGAEEC

交叉反应

人

产品特性

Antibody reactive against mammalian transfected lysate.

免疫原

TFAM (NP_003192.1, 1 a.a. ~ 246 a.a) full-length human protein.
anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody
TFAM 适用: 人, 小鼠, 兔, Cow, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 43-243) antibody
TFAM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 1-220) antibody
TFAM 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) antibody
KO Validated TFAM 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 227-246), (C-Term) antibody
TFAM 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 216-246), (C-Term) antibody
TFAM 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB27631 unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 1-246) antibody
TFAM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) antibody
TFAM 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 216-246) antibody
TFAM 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Transcription Factor A, Mitochondrial (TFAM) (AA 214-241), (N-Term) antibody
TFAM 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Takeda, Hasegawa, Ueha, Sakakibara, Kawamoto, Minamikawa, Sakai, Komori: "Decreased mitochondrial copy numbers in oral squamous cell carcinoma." in: Head & neck, Vol. 38, Issue 8, pp. 1170-5, (2016) (PubMed).

Morishita, Kawamoto, Hara, Onishi, Ueha, Minoda, Katayama, Takemori, Fukase, Kurosaka, Kuroda, Akisue: "AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway." in: International journal of oncology, Vol. 50, Issue 1, pp. 23-30, (2016) (PubMed).

Akbari, Sykora, Bohr: "Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells." in: Scientific reports, Vol. 5, pp. 12876, (2015) (PubMed).

Akbari, Keijzers, Maynard, Scheibye-Knudsen, Desler, Hickson, Bohr: "Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair." in: DNA repair, Vol. 16, pp. 44-53, (2014) (PubMed).

Gibellini, Pinti, Boraldi, Giorgio, Bernardi, Bartolomeo, Nasi, De Biasi, Missiroli, Carnevale, Losi, Tesei, Pinton, Quaglino, Cossarizza: "Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 12, pp. 5122-35, (2014) (PubMed).

Gispert, Parganlija, Klinkenberg, Dröse, Wittig, Mittelbronn, Grzmil, Koob, Hamann, Walter, Büchel, Adler, Hrabé de Angelis, Busch, Zell, Reichert, Brandt, Osiewacz, Jendrach, Auburger: "Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors." in: Human molecular genetics, Vol. 22, Issue 24, pp. 4871-87, (2013) (PubMed).

Rolland, Motori, Memar, Hench, Frank, Winklhofer, Conradt: "Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 32, pp. E2967-76, (2013) (PubMed).

Holmström, Iglesias-Gutierrez, Zierath, Garcia-Roves: "Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E731-9, (2012) (PubMed).

Aamann, Sorensen, Hvitby, Berquist, Muftuoglu, Tian, de Souza-Pinto, Scheibye-Knudsen, Wilson, Stevnsner, Bohr: "Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2334-46, (2010) (PubMed).
抗原

TFAM (Transcription Factor A, Mitochondrial (TFAM))

别名

TFAM

背景

Full Gene Name: transcription factor A, mitochondrial
Synonyms: MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA

基因ID

7019

NCBI登录号

NM_003201

途径

Chromatin Binding