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NBR1 抗体 (AA 2-96)

This anti-NBR1 antibody is a 小鼠 单克隆 antibody detecting NBR1 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 7+ publications.
产品编号 ABIN517601
发货至: 中国

Quick Overview for NBR1 抗体 (AA 2-96) (ABIN517601)

抗原

See all NBR1 抗体
NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

适用

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宿主

  • 15
  • 7
小鼠

克隆类型

  • 18
  • 4
单克隆

标记

  • 22
This NBR1 antibody is un-conjugated

应用范围

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  • 9
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Western Blotting (WB), ELISA

克隆位点

6B11
  • 抗原表位

    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 2-96

    原理

    Mouse monoclonal antibody raised against a partial recombinant NBR1.

    序列

    EPQVTLNVTF KNEIQSFLVS DPENTTWADI EAMVKVSFDL NTIQIKYLDE ENEEVSINSQ GEYEEALKMA VKQGNQLQMQ VHEGHHVVDE APPPV

    交叉反应

    人, 大鼠

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    NBR1 (NP_005890, 2 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Jiang, Hara-Kuge, Yamashita, Fujiki: "Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).

    Dowdle, Nyfeler, Nagel, Elling, Liu, Triantafellow, Menon, Wang, Honda, Pardee, Cantwell, Luu, Cornella-Taracido, Harrington, Fekkes, Lei, Fang, Digan, Burdick, Powers, Helliwell, DAquin, Bastien et al.: "Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. ..." in: Nature cell biology, Vol. 16, Issue 11, pp. 1069-79, (2014) (PubMed).

    Rué, López-Soop, Gelpi, Martínez-Vicente, Alberch, Pérez-Navarro: "Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease." in: Neurobiology of disease, Vol. 52, pp. 219-28, (2013) (PubMed).

    Deosaran, Larsen, Hua, Sargent, Wang, Kim, Lamark, Jauregui, Law, Lippincott-Schwartz, Brech, Johansen, Kim: "NBR1 acts as an autophagy receptor for peroxisomes." in: Journal of cell science, Vol. 126, Issue Pt 4, pp. 939-52, (2013) (PubMed).

    Wong, Bejarano, Rakshit, Lee, Hanson, Zaarur, Phillips, Sherman, Cuervo: "Molecular determinants of selective clearance of protein inclusions by autophagy." in: Nature communications, Vol. 3, pp. 1240, (2012) (PubMed).

    Mardakheh, Auciello, Dafforn, Rappoport, Heath: "Nbr1 is a novel inhibitor of ligand-mediated receptor tyrosine kinase degradation." in: Molecular and cellular biology, Vol. 30, Issue 24, pp. 5672-85, (2010) (PubMed).

    Mardakheh, Yekezare, Machesky, Heath: "Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling." in: The Journal of cell biology, Vol. 187, Issue 2, pp. 265-77, (2009) (PubMed).

  • 抗原

    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

    别名

    NBR1

    背景

    Full Gene Name: neighbor of BRCA1 gene 1
    Synonyms: 1A1-3B,KIAA0049,M17S2,MIG19

    基因ID

    4077

    NCBI登录号

    NM_005899

    途径

    Autophagy
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