NBR1 抗体 (AA 2-96)
Quick Overview for NBR1 抗体 (AA 2-96) (ABIN517601)
抗原
See all NBR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 2-96
-
原理
- Mouse monoclonal antibody raised against a partial recombinant NBR1.
-
序列
- EPQVTLNVTF KNEIQSFLVS DPENTTWADI EAMVKVSFDL NTIQIKYLDE ENEEVSINSQ GEYEEALKMA VKQGNQLQMQ VHEGHHVVDE APPPV
-
交叉反应
- 人, 大鼠
-
产品特性
- Antibody Reactive Against Recombinant Protein.
-
免疫原
- NBR1 (NP_005890, 2 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- In 1x PBS, pH 7.4
-
注意事项
- Aliquot to avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
-
: "Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).
: "Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. ..." in: Nature cell biology, Vol. 16, Issue 11, pp. 1069-79, (2014) (PubMed).
: "Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease." in: Neurobiology of disease, Vol. 52, pp. 219-28, (2013) (PubMed).
: "NBR1 acts as an autophagy receptor for peroxisomes." in: Journal of cell science, Vol. 126, Issue Pt 4, pp. 939-52, (2013) (PubMed).
: "Molecular determinants of selective clearance of protein inclusions by autophagy." in: Nature communications, Vol. 3, pp. 1240, (2012) (PubMed).
: "Nbr1 is a novel inhibitor of ligand-mediated receptor tyrosine kinase degradation." in: Molecular and cellular biology, Vol. 30, Issue 24, pp. 5672-85, (2010) (PubMed).
: "Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling." in: The Journal of cell biology, Vol. 187, Issue 2, pp. 265-77, (2009) (PubMed).
-
: "Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).
-
-