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HLA-ABC 抗体 (APC)

This APC-conjugated 小鼠 单克隆 anti-HLA-ABC antibody (Clone W6-32) specifically detects HLA-ABC in FACS. The antibody is reactive with 人, Baboon, Cynomolgus 和 猕猴 samples.
产品编号 ABIN5067853
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HLA-ABC 抗体 (APC) (ABIN5067853)

抗原

See all HLA-ABC 抗体
HLA-ABC

适用

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人, Baboon, Cynomolgus, 猕猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This HLA-ABC antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

W6-32
  • 原理

    Anti-HLA-ABC APC Antibody

    产品特性

    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human Leukocytes

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    HLA-ABC

    别名

    HLA-ABC

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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