Optimal working dilutions should be determined experimentally by the investigator.
限制
仅限研究用
状态
Liquid
储存条件
-20 °C
抗原
Nibrin (NBN)
别名
p95/NBS1
背景
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.