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Nibrin 抗体 (AA 350-400)

This 兔 多克隆 anti-Nibrin antibody specifically detects Nibrin in WB 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN504727
发货至: 中国
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Quick Overview for Nibrin 抗体 (AA 350-400) (ABIN504727)

抗原

See all Nibrin (NBN) 抗体
Nibrin (NBN)

适用

  • 119
  • 68
  • 43
  • 2
  • 1
  • 1
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  • 1
人, 小鼠

宿主

  • 135
  • 16

克隆类型

  • 95
  • 56
多克隆

标记

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This Nibrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 49
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    • 1
    AA 350-400

    交叉反应

    人, 小鼠

    纯化方法

    affinity purified

    免疫原

    Synthetic peptide made to an internal portion of the mouse protein (within AA 350-400). [Swiss-Prot# Q9R207].

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C
  • 抗原

    Nibrin (NBN)

    别名

    p95/NBS1

    背景

    The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

    UniProt

    Q9R207

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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