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NLRP3 抗体 (AA 1-200)

NLRP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027649
发货至: 中国
  • 抗原 See all NLRP3 抗体
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    抗原表位
    • 16
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200
    适用
    • 91
    • 57
    • 38
    • 23
    • 4
    • 2
    • 1
    • 1
    • 1
    宿主
    • 87
    • 11
    • 2
    • 1
    克隆类型
    • 85
    • 16
    多克隆
    标记
    • 44
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NLRP3 antibody is un-conjugated
    应用范围
    • 63
    • 40
    • 22
    • 13
    • 13
    • 10
    • 10
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial recombinant NALP3 protein (amino acids 1-200) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product NLRP3 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
    别名
    NALP3/CIAS1/Cryopyrin/PYPAF1 (NLRP3 产品)
    别名
    CIAS1 antibody, Nalp3 antibody, avp antibody, cias1 antibody, nalp3 antibody, pypaf1 antibody, agtavprl antibody, AGTAVPRL antibody, AII antibody, AVP antibody, C1orf7 antibody, CLR1.1 antibody, FCAS antibody, FCU antibody, MWS antibody, NALP3 antibody, PYPAF1 antibody, AII/AVP antibody, Cias1 antibody, Mmig1 antibody, Pypaf1 antibody, NLR family pyrin domain containing-like antibody, NLR family pyrin domain containing 3 antibody, NLR family, pyrin domain containing 3 L homeolog antibody, NLR family, pyrin domain containing 3 antibody, NLRPL antibody, NLRP3 antibody, nlrp3.L antibody, Nlrp3 antibody
    背景
    NALP3 (NACHT, LRR and PYD domains-containing protein 3), otherwise known as cryopyrin, is a member of the NLR (Nod-like-receptors) family. This is a pyrin-like protein, having N-terminal CARD or pyrin domains needed for homotypic protein-protein interaction, an intermediate nucleotide binding self-oligomerization NACHT domain and a C-terminal domain containing leucine-rich repeats (LRRs). NALP3 is a key component of innate immunity and its expression is restricted to immune cells and chondrocytes. It interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappa signaling, and it plays an important role in the regulation of inflammation, the immune response, and apoptosis.
    分子量
    114 kDa
    基因ID
    114548
    UniProt
    Q96P20
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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