VAV2 抗体 (AA 610-824)
Our Local Distributor
北京 101111
Quick Overview for VAV2 抗体 (AA 610-824) (ABIN5027629)
抗原
See all VAV2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 610-824
-
纯化方法
- Protein A Chromatography
-
免疫原
- A partial length recombinant VAV2 protein (amino acids 610-824) was used as the immunogen for this antibody.
-
亚型
- IgG
-
-
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 552-868) antibody
VAV2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F5D3 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyKD Validated VAV2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3270 unconjugated Recombinant Antibody
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56694 unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (Internal Region) antibodyVerified VAV2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 108-157), (pTyr142) antibodyVAV2 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人 宿主: 绵羊 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 570-700) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) (AA 612-691) antibodyVAV2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vav 2 Guanine Nucleotide Exchange Factor (VAV2) antibodyVAV2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1-2 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))
-
别名
- VAV2
-
背景
- Vav2 is a member of the Vav family that serves as a GRF (guanine nucleotide exchange factor) for the Rho family of Ras-related GTPases. It is widely expressed and regulates processes including cell migration, neuronal development and phagocytosis through interactions with different proteins. Vav2, a GEF for Rac1, RhoA, and Cdc42, is shown to be regulated by a phosphorylation-dependent interaction with PKL (Paxillin kinase linker). PKL is required for Vav2 activation downstream of integrin engagement and epidermal growth factor (EGF) stimulation. During the process of spinal neurons, the Vav2 activity is necessary for optimal neurite outgrowth and promotes branching by targeting GEF activity to branch points.
-
分子量
- 90 kDa
-
基因ID
- 7410
-
UniProt
- P52735
-
途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
-
