TAB3 抗体 (AA 1-385)
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Quick Overview for TAB3 抗体 (AA 1-385) (ABIN5027557)
抗原
See all TAB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-385
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant TAB3 protein (amino acids 1-350) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibody
TAB3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 361-712) antibodyTAB3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyVerified TAB3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyTAB3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 50-100) antibodyTAB3 适用: 人, 小鼠, 犬, 小鸡, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 4-6 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
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别名
- TAB3
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背景
- TAB3 (TGF-beta activated kinase 1/MAP3K7 binding protein 3) has CUE domain and RanBP2-type zinc finger (NZF) domains mediates binding to two consecutive 'Lys-63'-linked ubiquitins. It contains 712 amino acids. TAB3 is a mediator of MAP3K7 activation and it forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation of TNF or IL-1. This successive MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor and AP1 transcription factor. This protein shows interaction with TAB1, TAB2, MAP3K7, TRAF2 and TRAF6. It has 2 isoforms produced by alternative splicing. Isoform 2 may be an oncogenic factor. TAB3 involved in necrosis and tumors like disease.
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分子量
- 80 kDa
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基因ID
- 257397
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UniProt
- Q8N5C8
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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