S1PR1 抗体 (AA 1-320)
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北京 101111
Quick Overview for S1PR1 抗体 (AA 1-320) (ABIN5027519)
抗原
See all S1PR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-320
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant S1PR1 protein (amino acids 1-320) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB:4-6 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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别名
- S1PR1
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背景
- Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 plays an important role in cell migration reorganizing the actin cytoskeleton and by the formation of lamellipodia in response to the activity of sphingosine kinase SPHK1. Diseases associated with S1PR1 include follicular thyroid carcinoma and multiple sclerosis. It is mainly expressed on endothelial cells, vascular smooth muscle cells (low), fibroblasts, melanocytes and cells of epithelioid origin.
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分子量
- 40 kDa
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基因ID
- 1901
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UniProt
- P21453
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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