DDX58 抗体 (AA 1-220)
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北京 101111
Quick Overview for DDX58 抗体 (AA 1-220) (ABIN5027274)
抗原
See all DDX58 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-220
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant human RIG-I protein (amino acids 1-220) was used as the immunogen for this antibody.
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亚型
- IgG1 kappa
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 550-776) antibody
DDX58 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 1-211) antibodyDDX58 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (C-Term) antibodyVerified DDX58 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) antibodyDDX58 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 6C1 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 789-925) antibodyDDX58 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4G1B6 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (C-Term) antibodyDDX58 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 726-925) antibodyDDX58 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (N-Term) antibodyDDX58 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 200-250) antibodyDDX58 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) (AA 201-713) antibodyDDX58 适用: 人, 小鼠 WB, IHC, IP 宿主: 小鼠 Monoclonal Alme-1 unconjugated
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应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
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别名
- RIG-I
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背景
- RIG-I or Probable ATP-dependent RNA helicase DDX58 or simply DDX58 is a RNA helicase enzyme with two isoforms (106 and 101 kDa). RIG-I belongs to the DEAD/H box family and is involved in several cellular responses including RNA binding and alteration of RNA secondary structure. RIG-1 acts as sensor of viral nucleic acids thus activating a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines. Generally it remains as a monomer but upon activation by viral dsRNA it homomultimerizes and interacts with mitochondria antiviral signaling protein (MAVS/IPS1) which activating a cascade of reactions to produce specific interferon. RIG-1 is mostly expressed in vascular smooth cells.
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分子量
- 106 kDa
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基因ID
- 23586
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UniProt
- O95786
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途径
- Activation of Innate immune Response, Hepatitis C
抗原
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