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FLT1 抗体 (AA 102-321)

FLT1 适用: 人 IHC 宿主: 小鼠 Monoclonal ABM4A56 unconjugated
产品编号 ABIN5027202
发货至: 中国
  • 抗原 See all FLT1 抗体
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    抗原表位
    • 16
    • 12
    • 11
    • 11
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 102-321
    适用
    • 136
    • 65
    • 62
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 134
    • 29
    • 2
    • 1
    小鼠
    克隆类型
    • 136
    • 30
    单克隆
    标记
    • 85
    • 22
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLT1 antibody is un-conjugated
    应用范围
    • 104
    • 47
    • 43
    • 31
    • 22
    • 21
    • 17
    • 14
    • 14
    • 13
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant FLT1 protein (amino acids 102-321) was used as the immunogen for this antibody.
    克隆位点
    ABM4A56
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FLT1 Primary Antibody
  • 应用备注
    IHC: 5-10 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    别名
    FLT1 (FLT1 产品)
    别名
    FLT antibody, FLT-1 antibody, VEGFR-1 antibody, VEGFR1 antibody, FLT1 antibody, flt1b antibody, sFlt1 antibody, AI323757 antibody, Flt-1 antibody, fms related tyrosine kinase 1 antibody, FMS-related tyrosine kinase 1 antibody, vascular endothelial growth factor receptor 1 antibody, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, FMS-like tyrosine kinase 1 antibody, vascular endothelial growth factor receptor-1 antibody, FLT1 antibody, Flt1 antibody, CpipJ_CPIJ012087 antibody, flt1 antibody, FLT-1 antibody
    背景
    FLT-1 (fms-related tyrosine kinase 1) is an endogenous inhibitor of vascular endothelial growth factor, which is involved in cardiovascular remodeling and atherosclerosis development. It potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). FLT-1 is expressed on tumor cells and is implicated in tumor growth and progression. It is overexpressed in primary tumors and nodal metastasis. FLT-1 regulates monocyte migration, recruits endothelial cell progenitors, increases the adhesive properties of natural killer cells and induces growth factors. It is observed in many diseases with endothelial dysfunction, including pre-eclampsia and diabetic retinopathy, but whether it contributes to endothelial injury in IgAN requires further exploration.
    基因ID
    2321
    UniProt
    P17948
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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