FLT1 抗体 (AA 102-321)
Our Local Distributor
北京 101111
Quick Overview for FLT1 抗体 (AA 102-321) (ABIN5027202)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 102-321
-
纯化方法
- Protein G Chromatography
-
免疫原
- A partial length recombinant FLT1 protein (amino acids 102-321) was used as the immunogen for this antibody.
-
亚型
- IgG2b kappa
-
-
-
-
应用备注
- IHC: 5-10 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
-
别名
- FLT1
-
背景
- FLT-1 (fms-related tyrosine kinase 1) is an endogenous inhibitor of vascular endothelial growth factor, which is involved in cardiovascular remodeling and atherosclerosis development. It potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). FLT-1 is expressed on tumor cells and is implicated in tumor growth and progression. It is overexpressed in primary tumors and nodal metastasis. FLT-1 regulates monocyte migration, recruits endothelial cell progenitors, increases the adhesive properties of natural killer cells and induces growth factors. It is observed in many diseases with endothelial dysfunction, including pre-eclampsia and diabetic retinopathy, but whether it contributes to endothelial injury in IgAN requires further exploration.
-
基因ID
- 2321
-
UniProt
- P17948
-
途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
-