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FLT1 抗体 (AA 102-321)

This anti-FLT1 antibody is a 小鼠 单克隆 antibody detecting FLT1 in IHC. Suitable for 人.
产品编号 ABIN5027202
发货至: 中国

Quick Overview for FLT1 抗体 (AA 102-321) (ABIN5027202)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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宿主

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小鼠

克隆类型

  • 140
  • 55
单克隆

标记

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This FLT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

ABM4A56
  • 抗原表位

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    AA 102-321

    纯化方法

    Protein G Chromatography

    免疫原

    A partial length recombinant FLT1 protein (amino acids 102-321) was used as the immunogen for this antibody.

    亚型

    IgG2b kappa
  • 应用备注

    IHC: 5-10 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    FLT1

    背景

    FLT-1 (fms-related tyrosine kinase 1) is an endogenous inhibitor of vascular endothelial growth factor, which is involved in cardiovascular remodeling and atherosclerosis development. It potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). FLT-1 is expressed on tumor cells and is implicated in tumor growth and progression. It is overexpressed in primary tumors and nodal metastasis. FLT-1 regulates monocyte migration, recruits endothelial cell progenitors, increases the adhesive properties of natural killer cells and induces growth factors. It is observed in many diseases with endothelial dysfunction, including pre-eclampsia and diabetic retinopathy, but whether it contributes to endothelial injury in IgAN requires further exploration.

    基因ID

    2321

    UniProt

    P17948

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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