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DLL4 抗体 (AA 423-650)

This anti-DLL4 antibody is a 兔 多克隆 antibody detecting DLL4 in WB. Suitable for 人.
产品编号 ABIN5027156
发货至: 中国

Quick Overview for DLL4 抗体 (AA 423-650) (ABIN5027156)

抗原

See all DLL4 抗体
DLL4 (delta-Like 4 (DLL4))

适用

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宿主

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克隆类型

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多克隆

标记

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This DLL4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 423-650

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant DLL4 protein (amino acids 423-650) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 2-4 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    DLL4 (delta-Like 4 (DLL4))

    别名

    DLL4

    背景

    Dll4 (Delta-like 4), a membrane-bound Notch ligand, plays a fundamental role in vascular development and angiogenesis. It is highly expressed in capillary endothelial tip cells and is involved in suppressing neighboring stalk cells to become tip cells during angiogenesis. Dll4-Notch signaling is mediated either by direct cell-cell contact or by Dll4-containing exosomes from a distance. DLL4 signaling is extensively critical for tumor angiogenesis. Blockage of DLL4 signaling inhibits tumor growth by deregulating angiogenesis and promoting non productive angiogenesis. Additionally, DLL4 has been shown to help regulate the cellular actions of VEGF.

    分子量

    75 kDa

    基因ID

    54567

    UniProt

    Q9NR61

    途径

    Notch Signaling
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