CDC25A 抗体 (AA 190-484)
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北京 101111
Quick Overview for CDC25A 抗体 (AA 190-484) (ABIN5027104)
抗原
See all CDC25A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 190-484
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纯化方法
- Protein G Chromatography
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免疫原
- A partial length recombinant CDC25A protein (amino acids 190-484) was used as the immunogen for this antibody.
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亚型
- IgG2b kappa
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anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 235-484) antibody
CDC25A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer124) antibodyCDC25A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB07634 unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer75) antibodyCDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr507) antibodyCDC25A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer178) antibodyCDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr507) antibodyCDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer124) antibodyCDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 1-524) antibodyCDC25A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (Ser124) antibodyCDC25A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB59086 unconjugated
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (N-Term) antibodyCDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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别名
- CDC25A
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背景
- CDC25A is a dual specificity (tyr/thr) phosphatase and a putative upregulated c-Myc target gene. It is a regulator of the cell cycle required for progression from G1 to S phase. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. Overexpression of CDC25A bypassed the mechanism of cell cycle arrest, leading to enhanced DNA damage and decreased cell survival. Specific degradation of CDC25A is identified as part of the DNA damage checkpoint mechanism and suggested how CDC25A overexpression in human cancers might contribute to tumorigenesis.
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分子量
- 59 kDa
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基因ID
- 993
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UniProt
- P30304
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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