电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CDC25A 抗体 (AA 190-484)

This anti-CDC25A antibody is a 小鼠 单克隆 antibody detecting CDC25A in WB 和 IHC. Suitable for 人.
产品编号 ABIN5027104
发货至: 中国

Quick Overview for CDC25A 抗体 (AA 190-484) (ABIN5027104)

抗原

See all CDC25A 抗体
CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

适用

  • 200
  • 70
  • 54
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1

宿主

  • 211
  • 5
小鼠

克隆类型

  • 212
  • 4
单克隆

标记

  • 97
  • 17
  • 14
  • 13
  • 9
  • 9
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
This CDC25A antibody is un-conjugated

应用范围

  • 174
  • 105
  • 56
  • 40
  • 40
  • 31
  • 20
  • 16
  • 15
  • 8
  • 7
  • 6
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

ABM4A46
  • 抗原表位

    • 32
    • 26
    • 19
    • 17
    • 15
    • 13
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-484

    纯化方法

    Protein G Chromatography

    免疫原

    A partial length recombinant CDC25A protein (amino acids 190-484) was used as the immunogen for this antibody.

    亚型

    IgG2b kappa
  • 应用备注

    WB: 2-4 μg/mL, IHC: 5 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

    别名

    CDC25A

    背景

    CDC25A is a dual specificity (tyr/thr) phosphatase and a putative upregulated c-Myc target gene. It is a regulator of the cell cycle required for progression from G1 to S phase. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. Overexpression of CDC25A bypassed the mechanism of cell cycle arrest, leading to enhanced DNA damage and decreased cell survival. Specific degradation of CDC25A is identified as part of the DNA damage checkpoint mechanism and suggested how CDC25A overexpression in human cancers might contribute to tumorigenesis.

    分子量

    59 kDa

    基因ID

    993

    UniProt

    P30304

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
You are here:
Chat with us!