Caspase 12 抗体 (AA 100-321)
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北京 101111
Quick Overview for Caspase 12 抗体 (AA 100-321) (ABIN5027075)
抗原
See all Caspase 12 (CASP12) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-321
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant Caspase-12 protein (amino acids 100-321) was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
- WB: 4-6 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
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别名
- Caspase-12
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背景
- Caspase 12 belongs to a family of enzymes called caspases that is highly related to members of the ICE subfamily. Other caspases cleave their substrates at C-terminal aspartic acid residue but caspase 12 does not have protease properties rather it processes inflammatory cytokines. It is involved in the activation cascade of caspases responsible for apoptosis execution. Diseases associated with CASP12 include sepsis and prion disease. Caspase 12 is mainly expressed in skeletal muscle and lung.
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分子量
- 27 kDa
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基因ID
- 101000000
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UniProt
- Q6UXS9
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途径
- Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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