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beta Arrestin 1 抗体 (AA 150-318)

This anti-beta Arrestin 1 antibody is a 兔 多克隆 antibody detecting beta Arrestin 1 in WB. Suitable for 人.
产品编号 ABIN5027057
发货至: 中国

Quick Overview for beta Arrestin 1 抗体 (AA 150-318) (ABIN5027057)

抗原

See all beta Arrestin 1 (ARRB1) 抗体
beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

适用

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宿主

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克隆类型

  • 80
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多克隆

标记

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This beta Arrestin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 150-318

    纯化方法

    Protein A Chromatography

    免疫原

    A partial length recombinant Beta-arrestin 1 protein (amino acids 150-318) was used as the immunogen for this antibody.

    亚型

    IgG
  • 应用备注

    WB: 2-4 μg/mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % BSA, PH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原

    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

    别名

    Beta-arrestin 1

    背景

    Beta-arrestin 1, a member of arrestin family, is a cofactor of beta-adrenergic receptor kinase (BARK) in beta-adrenergic receptor desensitization and resensitization process. Beta-arrestin 1 acts as endocytic adapter for internalization of many G-protein coupled receptors. Beta-arrestin 1 is also associated with many other cellular processes like ubiquitination and down-regulation of the insulin-like growth factor-1 receptor, synaptic transmission in photoreceptor cells, working as a scaffold protein in G-protein coupled receptor signaling pathways. Two isoforms of beta-arrestin 1 have been identified, isoform 1 (47 kDa) and isoform 2 (46 kDa). Beta-arrestin 1 is highly expressed in liver, kidney, lungs and testes.

    分子量

    47 kDa

    基因ID

    408

    UniProt

    P49407

    途径

    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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