DAPK3 抗体 (Center)
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北京 101111
Quick Overview for DAPK3 抗体 (Center) (ABIN501161)
抗原
See all DAPK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects DAPK3 / ZIPK at Center.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- ZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1: 500 to 1: 1000. An approximate 40 kDa band can be detected, whichrepresents the pro-enzyme of DNase II. Immunflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
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别名
- DAPK3 / ZIPK
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背景
- Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues .Synonyms: DAP kinase 3, DAP-like kinase, DLK, Death-associated protein kinase 3, ZIP-kinase
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基因ID
- 1613
抗原
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