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DAPK3 抗体 (Center)

The 兔 多克隆 anti-DAPK3 antibody is suitable to detect DAPK3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF 和 EIA.
产品编号 ABIN501161
发货至: 中国
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Quick Overview for DAPK3 抗体 (Center) (ABIN501161)

抗原

See all DAPK3 抗体
DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DAPK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    This antibody detects DAPK3 / ZIPK at Center.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography

    免疫原

    ZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1: 500 to 1: 1000. An approximate 40 kDa band can be detected, whichrepresents the pro-enzyme of DNase II. Immunflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

    别名

    DAPK3 / ZIPK

    背景

    Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues .Synonyms: DAP kinase 3, DAP-like kinase, DLK, Death-associated protein kinase 3, ZIP-kinase

    基因ID

    1613
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