电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TRIM5 抗体 (C-Term, Isoform alpha)

This anti-TRIM5 antibody is a 兔 多克隆 antibody detecting TRIM5 in WB, IF 和 EIA. Suitable for 人 和 猕猴.
产品编号 ABIN501054
发货至: 中国

Quick Overview for TRIM5 抗体 (C-Term, Isoform alpha) (ABIN501054)

抗原

See all TRIM5 抗体
TRIM5 (Tripartite Motif Containing 5 (TRIM5))

适用

  • 39
  • 3
  • 2
  • 1
人, 猕猴

宿主

  • 34
  • 4
  • 1

克隆类型

  • 35
  • 4
多克隆

标记

  • 30
  • 3
  • 2
  • 2
  • 1
  • 1
This TRIM5 antibody is un-conjugated

应用范围

  • 33
  • 23
  • 12
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, Isoform alpha

    特异性

    This antibody detects TRIM5 / RNF88 at C-term.

    交叉反应 (详细)

    Species reactivity (expected):Rhesus monkeySpecies reactivity (tested):Human

    纯化方法

    Paptide affinity chromatography

    免疫原

    TRIM5 alpha antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of rhesus monkey TRIM5 alpha.

    亚型

    IgG
  • 应用备注

    ELISA. Immunoflourescence. Western blot: 1 to 2 μg/mL. A band at approximately 55 kDa can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TRIM5 (Tripartite Motif Containing 5 (TRIM5))

    别名

    TRIM5 / RNF88

    背景

    TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region (1). TRIM5 has six alternately spliced isoforms, the longest of which is the ? variant which also contains a carboxy-terminal B30.2 (SPRY) domain (1). Expression of TRIM5alpha variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1 (2,3), albeit at differing efficiencies. All TRIM5alpha variants could inhibit at least two different retroviruses, but not from those viruses isolated from the same species, suggesting that TRIM5alpha acts as a natural barrier to cross-species retrovirus transmission (3).Synonyms: RING finger protein 88, Tripartite motif-containing protein 5

    基因ID

    85363

    NCBI登录号

    NP_149023

    途径

    Activation of Innate immune Response
You are here:
Chat with us!