TRIM5 抗体 (Isoform alpha, Middle Region)
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- 抗原 See all TRIM5 抗体
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
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抗原表位
- Isoform alpha, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects TRIM5 / RNF88 alpha at Center.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- TRIM5 alpha antibody was raised against a synthetic peptide corresponding to amino acids near the mid-region of human TRIM5 alpha.
- 亚型
- IgG
- Top Product
- Discover our top product TRIM5 Primary Antibody
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anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibody
Verified TRIM5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3B11H2 unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 1-493) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (C-Term) antibodyTRIM5 适用: 人, 猴 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (Internal Region) antibodyTRIM5 适用: 人, 猴 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (C-Term) antibodyTRIM5 适用: 人, 猴 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 35-84) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 1 to 2 μg/mL. A band at approximately 55 kDa can be detected. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- 别名
- TRIM5 / RNF88 (TRIM5 产品)
- 别名
- TRIM5 antibody, RNF88 antibody, TRIM5alpha antibody, EG667823 antibody, Gm8833 antibody, RGD1304579 antibody, tripartite motif containing 5 antibody, tripartite motif-containing 5 antibody, TRIM5 antibody, Trim5 antibody
- 背景
- TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region . TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5alpha variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. All TRIM5alpha variants could inhibit at least two different retroviruses, but not from those viruses isolated from the same species, suggesting that TRIM5alpha acts as a natural barrier to cross-species retrovirus transmission.Synonyms: RING finger protein 88, Tripartite motif-containing protein 5
- 基因ID
- 85363
- NCBI登录号
- NP_149023
- 途径
- Activation of Innate immune Response
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