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TICAM1 抗体 (C-Term)

This anti-TICAM1 antibody is a 兔 多克隆 antibody detecting TICAM1 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN501042
发货至: 中国

Quick Overview for TICAM1 抗体 (C-Term) (ABIN501042)

抗原

See all TICAM1 抗体
TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TICAM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects TICAM1 / TRIF.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Ion exchange chromatography

    免疫原

    TRIF antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRIF.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 2 to 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

    别名

    TICAM1 / TRIF

    背景

    TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3 (5). TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-kappaB (6).Synonyms: PRVTIRB, Proline-rich vinculin and TIR domain-containing protein B, Putative NF-kappa-B-activating protein 502H, TICAM-1, TIR domain-containing adapter molecule 1, Toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta

    基因ID

    148022

    NCBI登录号

    NP_891549

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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