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PSMA7 抗体 (AbBy Fluor® 750)

This anti-PSMA7 antibody is a 兔 多克隆 antibody detecting PSMA7 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5009343
发货至: 中国

Quick Overview for PSMA7 抗体 (AbBy Fluor® 750) (ABIN5009343)

抗原

See all PSMA7 抗体
PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

适用

  • 55
  • 26
  • 17
  • 1
人, 小鼠, 大鼠

宿主

  • 46
  • 9

克隆类型

  • 47
  • 8
多克隆

标记

  • 28
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PSMA7 antibody is conjugated to AbBy Fluor® 750

应用范围

  • 46
  • 21
  • 16
  • 12
  • 8
  • 8
  • 8
  • 4
  • 4
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 7

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

    别名

    PSMA7/Proteasome 20S alpha 7

    背景

    Synonyms: C6 antibody HSPC, Proteasome prosome macropain subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, Proteasome subunit alpha type-7, Proteasome subunit RC6 1, Proteasome subunit RC6-1, Proteasome subunit XAPC7, PSA7_HUMAN, PSMA7, RC6 1, XAPC7.

    Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

    基因ID

    5688

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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