MAP3K7 抗体 (N-Term)
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Quick Overview for MAP3K7 抗体 (N-Term) (ABIN500865)
抗原
See all MAP3K7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects TAK1 / MAP3K7 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Human TAK1 / MAP3K7 (N-Terminus) Peptide
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 300-470) antibody
MAP3K7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibodyMAP3K7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Internal Region) antibodyVerified MAP3K7 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Thr187) antibodyMAP3K7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pSer412) antibodyMAP3K7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) antibodyKD Validated MAP3K7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2395 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibodyMAP3K7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 471-579) antibodyMAP3K7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C9 unconjugated
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应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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别名
- TAK1 / MAP3K7
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背景
- TAK1 (TGF-β activated protein kinase 1) is a widely expressed enzyme originally identified as a mitogen-activated protein kinase kinase kinase (MAP3K7) (1). It has since been shown to mediate various intracellular signaling pathways, such as those induced by TGF-Β and members of the Toll-IL-1R (TIR) superfamily (2), thus acting as an intermediate in both proliferative and innate and adaptive immune responses (3). TAK1 is normally present in cells in a complex with TAK1-binding protein 1 (TAB1) and either TAB2 or TAB3 (4,5). Association with TAB1 triggers TAK1 kinase activity by inducing TAK1 autophosphorylation (6), while TAB2 and possibly TAB3 may contribute to SAPK2a/p38a-mediated feedback inhibition of TAK1 activity (5).Synonyms: Mitogen-activated protein kinase kinase kinase 7, TAK-1, TAK1, TGF-beta-activated kinase 1, Transforming growth factor-beta-activated kinase 1
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基因ID
- 6885
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途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
抗原
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