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PAK3 抗体 (pSer139) (AbBy Fluor® 750)

This anti-PAK3 antibody is a 兔 多克隆 antibody detecting PAK3 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN5008288
发货至: 中国

Quick Overview for PAK3 抗体 (pSer139) (AbBy Fluor® 750) (ABIN5008288)

抗原

See all PAK3 抗体
PAK3

适用

  • 78
  • 32
  • 21
  • 3

宿主

  • 72
  • 5
  • 2

克隆类型

  • 71
  • 9
多克隆

标记

  • 39
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This PAK3 antibody is conjugated to AbBy Fluor® 750

应用范围

  • 60
  • 38
  • 31
  • 12
  • 12
  • 9
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 16
    • 8
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human PAK3 around the phosphorylation site of (Ser139)

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PAK3

    别名

    PAK3

    背景

    Synonyms: PAK3_HUMAN, Beta PAK, bPAK, CDKN1A, hPAK3, Mental retardation X linked 30, MRX30, MRX47, Oligophrenin 3, OPHN3, p21 activated kinase 3, p21 CDKN1A activated kinase 3, PAK-3, PAK3 p21 protein Cdc42/Rac-activated kinase 3, PAK3beta, Pak65alpha, Pak65beta, Serine threonine protein kinase PAK 3, Stk4.

    Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, and PAK 3 (also known as alpha PAK, gamma PAK, and beta PAK, respectively). These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 (SH3) domains, and caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), catalyzed by Cdc42, is required for activation of PAK.

    基因ID

    5063
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