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SLUG 抗体 (Center)

SNAI2 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500780
发货至: 中国
  • 抗原 See all SLUG (SNAI2) 抗体
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 51
    • 19
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 11
    克隆类型
    • 41
    • 9
    多克隆
    标记
    • 33
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This SLUG antibody is un-conjugated
    应用范围
    • 28
    • 20
    • 12
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SNAI2 / SLUG at center. It has no cross-reactivity to Snail protein.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse
    纯化方法
    Peptide affinity chromatography
    免疫原
    Slug antibody was raised against a 13 amino acid peptide from near the center of human Slug.
    亚型
    IgG
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  • 应用备注
    ELISA. Western blot: 1 to 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    别名
    SNAI2 / SLUG (SNAI2 产品)
    别名
    Slug antibody, Slugh antibody, Snail2 antibody, snail family transcriptional repressor 2 antibody, snail family zinc finger 2 antibody, Snai2 antibody
    背景
    Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemapoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family.Synonyms: Neural crest transcription factor Slug, Protein snail homolog 2, SLUGH, Zinc finger protein SNAI2
    基因ID
    6591
    UniProt
    O43623
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