SCO2 抗体 (C-Term)
Quick Overview for SCO2 抗体 (C-Term) (ABIN500688)
抗原
See all SCO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects SCO2.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- SCO2 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human SCO2.
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亚型
- IgG
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anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-130) antibody
SCO2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) antibodySCO2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-130) antibodySCO2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 42-266) antibodySCO2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-266) antibodySCO2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
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别名
- SCO2
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背景
- Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.Synonyms: Synthesis of cytochrome c oxidase 2, cytochrome oxidase deficient homolog 2
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基因ID
- 3184203
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UniProt
- O43819, Q5KW01
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途径
- Transition Metal Ion Homeostasis, Warburg Effect
抗原
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