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Manic Fringe 抗体 (AA 221-321) (AbBy Fluor® 750)

This AbBy Fluor® 750-conjugated 兔 多克隆 anti-Manic Fringe antibody specifically detects Manic Fringe in FACS, IF (cc) 和 IF (p). The antibody is reactive with 小鼠 samples.
产品编号 ABIN5006485
发货至: 中国
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Quick Overview for Manic Fringe 抗体 (AA 221-321) (AbBy Fluor® 750) (ABIN5006485)

抗原

See all Manic Fringe (MFNG) 抗体
Manic Fringe (MFNG) (MFNG)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Manic Fringe antibody is conjugated to AbBy Fluor® 750

应用范围

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Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 221-321

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep,Horse,Chimpanzee

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Manic Fringe (MFNG) (MFNG)

    别名

    Manic Fringe/MFNG

    背景

    Synonyms: 3-N-acetylglucosaminyltransferase manic fringe, Beta-1, Beta-1,3-N-acetylglucosaminyltransferase manic fringe, MFNG, MFNG_HUMAN, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.

    Background: Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

    基因ID

    4242

    途径

    Notch Signaling
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