RIPK3 抗体 (AA 473-486)
Quick Overview for RIPK3 抗体 (AA 473-486) (ABIN500612)
抗原
See all RIPK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 473-486
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特异性
- This antibody detects RIP3.
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交叉反应 （详细）
- Species reactivity (tested):Mouse, Rat.
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纯化方法
- Peptide Affinity Chromatography
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免疫原
- RIP3 antibody was raised against a peptide corresponding to amino acids 473 to 486 of Murine RIP3.
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亚型
- IgG
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anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-120) antibody
RIPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (N-Term) antibodyRIPK3 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 61-91) antibodyRIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 16-239) antibodyRIPK3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 489-518) antibodyRIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) antibodyRIPK3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-217) antibodyRIPK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-518) antibodyRIPK3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-120) antibodyRIPK3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 168-217) antibodyRIPK3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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别名
- RIPK3 / RIP3
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背景
- Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3 (1-3). RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kB activation. Overexpression of RIP3 induces apoptosis and NF-kappaB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues (2,3).Synonyms: RIP-3, RIP-like protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3
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分子量
- 57 kDa
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基因ID
- 56532
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UniProt
- Q9QZL0
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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