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PAK7 抗体 (Center)

This anti-PAK7 antibody is a 兔 多克隆 antibody detecting PAK7 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN500443
发货至: 中国

Quick Overview for PAK7 抗体 (Center) (ABIN500443)

抗原

See all PAK7 抗体
PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

适用

  • 44
  • 17
  • 15
  • 1

宿主

  • 47

克隆类型

  • 47
多克隆

标记

  • 22
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
This PAK7 antibody is un-conjugated

应用范围

  • 31
  • 25
  • 23
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 8
    • 4
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    特异性

    This antibody detects PAK5.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Peptide affinity chromatography

    免疫原

    13 amino acid peptide from near the center of human PAK5

    亚型

    IgG
  • 应用备注

    ELISA. Western blot. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

    别名

    PAK7 / PAK5

    背景

    The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.Synonyms: KIAA1264, PAK-5, PAK-7, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, p21-activated kinase 7

    基因ID

    57144

    UniProt

    Q9P286
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