PAK7 抗体 (Center)
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北京 101111
Quick Overview for PAK7 抗体 (Center) (ABIN500443)
抗原
See all PAK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects PAK5.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- 13 amino acid peptide from near the center of human PAK5
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亚型
- IgG
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anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157) antibody
PAK7 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1235 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 621-719) antibodyPAK7 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157), (N-Term) antibodyPAK7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34659 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 26-55), (N-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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别名
- PAK7 / PAK5
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背景
- The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.Synonyms: KIAA1264, PAK-5, PAK-7, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, p21-activated kinase 7
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基因ID
- 57144
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UniProt
- Q9P286
抗原
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