ORAI3 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for ORAI3 抗体 (C-Term) (ABIN500427)
抗原
See all ORAI3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects ORAI3 at C-term. It i predicted to have no cross-reactivity to ORAI1 or ORAI2.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- ORAI3 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ORAI3.
-
亚型
- IgG
-
-
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) antibody
ORAI3 适用: 人 WB 宿主: 兔 Monoclonal 25GB4720 unconjugated Recombinant Antibody
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (AA 1-30) antibodyORAI3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2H2G9 unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (N-Term) antibodyORAI3 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
-
别名
- ORAI3
-
背景
- Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.Synonyms: ORAI-3, TMEM142C, Transmembrane Protein 142C
-
基因ID
- 93129
-
UniProt
- Q9BRQ5
抗原
-
